Seaweeds are one of the most important living resources of the ocean and are one of the largest producers of biomass in the marine environment. They produce a wide variety of chemically active metabolites in their surroundings, potentially as an aid to protect themselves against the other settling organisms. These biogenic molecules impart the uniqueness of chemical diversity in seaweeds compared to other plants. Which owe them multitude of medicinal properties, because of that they are often been used as a food for people who are sick and has been credited with health-giving properties and have gained importance as medicinal sources. Present review highlights a state of art on the medicinal value of seaweeds and their exploitation scenario on a global scale.