Integrated multi-trophic aquaculture involves cultivating fed species with extractive species that utilize wastes from aquaculture for their growth. All components have commercial value, as well as roles in biomitigating. The IMTA concept should also be understood within an integrated land/coastal aquaculture ecosystem approach. Regulatory frameworks and financial incentives may be required to fully realize the benefits of IMTA systems. Differentiation of IMTA products through traceability and ecolabeling will be key in their promotion.