Natural products against cancer: Review on phytochemicals from marine sources in preventing cancer

Abstract: 

Marine natural products have as of now been acknowledged as the most important source of bioactive substances and drug leads. Marine flora and fauna, such as algae, bacteria, sponges, fungi, seaweeds, corals, diatoms, ascidian etc. are important resources from oceans, accounting for more than 90% of the total oceanic biomass. They are taxonomically different with huge productive and are pharmacologically active novel chemical signatures and bid a tremendous opportunity for discovery of new anti-cancer molecules. The water bodies a rich source of potent molecules which improve existence suitability and serve as chemical shield against microbes and little or huge creatures. These molecules have exhibited a range of biological properties antioxidant, antibacterial, antitumour etc. In spite of huge resources enriched with exciting chemicals, the marine floras and faunas are largely unexplored for their anticancer properties. In recent past, numerous marine anticancer compounds have been isolated, characterized, identified and are under trials for human use. In this write up we have tried to compile about marine-derived compounds anticancer biological activities of diverse flora and fauna and their underlying mechanisms and the generous raise in these compounds examined for malignant growth treatment in the course of the most recent quite a long while.

Author(s): 
Adil Farooq Wali
Sabhiya Majid
Shabhat Rasool
Samar Bassam Shehada
Shahad Khalid Abdulkareem
Aimen Firdous
Saba Beigh
Sheeba Shakeel
Saima Mushtaq
Imra Akbar
Hassan Madhkali
Muneeb U. Rehman
Keywords: 
Marine
Anti-cancer
Natural products
Corals
Marine herbs
Seaweeds
Article Source: 
Saudi Pharmaceutical Journal Volume 27, Issue 6, September 2019, Pages 767-777
Category: 
Basic Biology
Seaweed composition
Uses of Seaweeds: Miscellaneous