Anticancer and Antitumor Potential of Fucoidan and Fucoxanthin, Two Main Metabolites Isolated from Brown Algae

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Abstract: 

Seaweed is one of the largest producers of biomass in marine environment and is a rich arsenal of active metabolites and functional ingredients with valuable beneficial health effects. Being a staple part of Asian cuisine, investigations on the crude extracts of Phaeophyceae or brown algae revealed marked antitumor activity, eliciting a variety of research to determine the active ingredients involved in this potential. The sulfated polysaccharide of fucoidan and carotenoid of fucoxanthin were found to be the most important active metabolites of brown algae as potential chemotherapeutic or chemopreventive agents. This review strives to provide detailed account of all current knowledge on the anticancer and antitumor activity of fucoidan and fucoxanthin as the two major metabolites isolated from brown algae. 

Author(s): 
Soheil Zorofchian Moghadamtousi
Hamed Karimian
Ramin Khanabdali
Mahboubeh Razavi
Mohammad Firoozinia
Keivan Zandi
Habsah Abdul Kadir
Link / Ref: 
ResearchGate
Attachment: 
PDF icon Anticancer and Antitumor Potential of Fucoidan and Fucoxanthin, Two Main Metabolites Isolated from Brown Algae.pdf
Article Source: 
The Scientific World Journal, Vol. 2014
Category: 
Seaweed composition
Uses of Seaweeds: Chemicals
Uses of Seaweeds: Miscellaneous