A significant challenge to the expansion of aquaculture production is controlling the outbreak of disease. Many farmers who experience the potential loss of stock from disease may choose to use chemotherapeutic agents to minimize their loss. It is generally understood that a disease in aquaculture is a combination of the health of the animal, the condition of the environment and the presence of a pathogen. From this concept there are a number of precautionary measures that farmers may practice to minimize disease outbreaks. The principles of Hazard Analysis Critical Control Point (HACCP) may be useful risk management tools to reduce pathogens, animal stress and the need for chemotherapeutic agents to control disease outbreaks on the farm.